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Find Relief from Depression with Ketamine & Spravato® Therapy

Fast-acting relief with medically supervised treatments and ongoing support for lasting mental wellness.

Over 8,000 Patients Treated with 84% Success Rate

Dr. Glen Brooks, the nation’s leading ketamine therapy practitioner and founder of NYKI, has been treating depression, anxiety, PTSD, and chronic pain for over 40 years.

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Ketamine: The Breakthrough Treatment

Ketamine infusion treatments are the gold standard for addressing drug-resistant depression, anxiety, PTSD and numerous other mental illnesses

Ketamine: The Breakthrough Treatment

Ketamine infusion treatments are the gold standard for addressing drug-resistant depression, anxiety, PTSD and numerous other mental illnesses

Depression Treatment New York 1

Find Fast Relief with Ketamine Therapy

Our treatments can provide noticeable improvements within hours. Don’t wait any longer—take control of your mental health today.

Success Stories from Our Patients

Depression Treatment Covered by Insurance

For many patients, cost can feel like one of the biggest barriers to getting help. NY Ketamine Infusions works with a growing list of insurance plans to help make SPRAVATO® treatment more accessible for qualified patients in New York City and Long Island.

If you have been diagnosed with depression and have not found enough relief from traditional antidepressants, insurance-covered SPRAVATO® treatment may be an option worth exploring.

We Can Help Verify Your Benefits

Our team can help review your insurance information, explain next steps, and determine whether SPRAVATO® may be covered under your plan.

Verify Your Insurance Refer Someone
Depression Treatment New York 1

What to Expect at NY Ketamine Infusions

Personalized care in a private, compassionate setting.

At NY Ketamine Infusions, we tailor each treatment plan to your specific needs. Our experienced team provides personalized care in a private, comfortable environment, ensuring a safe and supportive experience for depression, anxiety, chronic pain, and more.

As featured in

Reviews

they accept Medicaid for Spravatoprivate treatment rooms + apple juicestaff are kind and professional ❤️
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Leevin M.
3/11/2026
A treatment that actually works I spent years taking medication and therapy for depression and nothing worked. I did seven IV treatments and my life has drastically changed for the better. The staff is very nice and extremely supportive. On my final IV session I had a breakthrough which was very overwhelming and one of the nurses held my hand and stayed with me until I was able to calm down and feel safe. The best money I spent on my mental health was at NY Ketamine.
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Andres M.
1/29/2026
I have had an extremely positive experience referring my patients here. I recently met the new medical director, Dr. M., who was lovely and listened to my concerns for a particular patient. My patient was promptly given an consultation and started infusions shortly there after, and shared with me having a positive experience at NYK. I have visited the facility myself over a year ago and met with Dr. Glatter and some other doctors and I can that it is super clean and welcoming. I plan to continue to refer my patients here.
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Keeley T.
12/31/2025
LIFESAVING... quite literally! I am 20 years old. Ketamine pulled me out of a suicidal depression. With other med changes post Ketamine I have been thriving for months. Staff is extremely nice, especially Nicole, who made the process so comforting for my mom and me. Any new patient with questions, feel free to reach out to me!
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Joseph P.
9/02/2025
I've been going to NY Ketamine for a several months. My life has been unimaginably transformed. Where there was depression and despair and hopelessness there is now hope and peace and confidence. I recommend the facility and wonderful team wholeheartedly and I am so grateful that they exist.
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Michael S.
2/22/2025
This is the top tier ketamine doctor in the US. His evaluation, pretreatment discussion, dosing, timing is impeccable. I am a patient and physician and NYKI is the only center to go to for ketamine infusion.
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sydney s.
10/02/2024
Ketamine & SPRAVATO® Treatment FAQs

Frequently Asked Questions About Ketamine & SPRAVATO® Treatment

Learn about ketamine and SPRAVATO® treatment for depression and treatment-resistant depression, including how quickly treatment may work, how long benefits may last, treatment costs, insurance coverage, and accessing care in New York City and Long Island.

How quickly does ketamine work for depression?

Ketamine can produce antidepressant effects more rapidly than conventional antidepressant medications for some people with depression, particularly treatment-resistant depression. Some patients may notice changes within hours or during the first few days after treatment, although response time and degree of improvement vary from person to person.

Ketamine works through pathways involving glutamate signaling, NMDA and AMPA receptors, and mechanisms associated with synaptic plasticity. Learn more about how ketamine works for depression .

How long do the antidepressant effects of ketamine last?

The duration of ketamine's antidepressant effects varies by patient. Some people experience improvement that lasts for days or weeks after an individual treatment, while others may require a series of treatments followed by individualized maintenance therapy.

Factors such as the severity and duration of depression, previous treatment response, medical history, medications, and individual response can influence how long benefits persist.

How many ketamine treatments are typically needed for depression?

Ketamine treatment for depression is generally administered as a series rather than as a single isolated treatment. The appropriate number and frequency of infusions varies based on diagnosis, symptoms, prior treatment history, response, and the treating clinician's recommendations.

Learn more about ketamine treatment for depression .

How long can the benefits of ketamine treatment persist?

Benefits from ketamine treatment can persist beyond the immediate treatment period, but the duration differs substantially between patients. Some people experience sustained improvement after an initial treatment series, while others may benefit from periodic maintenance treatments.

Long-term treatment decisions are typically based on symptom response and ongoing clinical evaluation rather than a fixed treatment schedule.

Does ketamine work for treatment-resistant depression?

Ketamine is commonly considered for people with depression who have not experienced adequate improvement from conventional treatments. This is often referred to as treatment-resistant depression, or TRD.

Because ketamine acts through different neurobiological pathways than traditional antidepressants, it may provide another treatment option for appropriately selected patients. Learn more about treatment-resistant depression treatment in New York .

How much does ketamine treatment cost in New York?

The cost of ketamine treatment depends on the type of treatment and the number of sessions recommended as part of an individual treatment plan. IV ketamine treatment is typically paid directly by the patient, although financing or discount options may sometimes be available.

For current pricing and payment information, visit ketamine treatment fees and insurance .

Is ketamine treatment for depression covered by insurance?

Coverage depends on the treatment being provided and the patient's insurance benefits. IV ketamine for mental health conditions is often not covered by insurance.

SPRAVATO® (esketamine), by contrast, is an FDA-approved treatment for certain depression indications and may be covered for eligible patients. Learn more about insurance-covered depression treatment in New York .

What is the difference between ketamine and SPRAVATO®?

IV ketamine and SPRAVATO® are related treatments, but they are not the same medication or delivered in the same way. IV ketamine is administered intravenously in a medically supervised setting, while SPRAVATO® contains esketamine and is administered as a nasal spray under medical supervision.

SPRAVATO® is FDA-approved for specific depression indications, while IV ketamine for depression is used off-label based on clinical evidence and physician judgment. The most appropriate option depends on diagnosis, treatment history, insurance coverage, medical history, and individual clinical needs.

Learn more about SPRAVATO® treatment .

Is SPRAVATO® covered by insurance?

SPRAVATO® may be covered by commercial insurance, Medicare, Medicaid, or other health plans for patients who meet the medical and plan-specific eligibility requirements. Coverage varies by insurer, and prior authorization may be required.

NY Ketamine Infusions can help eligible patients understand coverage requirements before treatment. Learn more about SPRAVATO® insurance coverage .

Where can I get SPRAVATO® treatment in NYC or Long Island?

NY Ketamine Infusions provides medically supervised SPRAVATO® treatment for eligible patients in New York City and Long Island. Patients are evaluated before treatment to determine whether SPRAVATO® is clinically appropriate and whether insurance authorization is required.

Patients seeking care on Long Island can learn more about SPRAVATO® treatment on Long Island , or visit our treatment locations to explore available care options.

Treatment response and insurance eligibility vary by patient. A consultation with a qualified medical professional is required to determine whether ketamine or SPRAVATO® treatment is appropriate for an individual's condition, treatment history, and medical needs.

Ketamine & Spravato Treatment Near

Financial District Tribeca SoHo Chinatown Lower East Side Battery Park City Greenwich Village West Village East Village NoHo Flatiron District Chelsea Brooklyn DUMBO Downtown Brooklyn Williamsburg Jersey City Hoboken Melville West Hills South Huntington Huntington Station Dix Hills Wheatley Heights Wyandanch Old Bethpage Plainview Woodbury Farmingdale East Farmingdale Deer Park Bethpage Syosset Huntington Cold Spring Harbor Greenlawn Elwood North Babylon

NY Ketamine Infusions provides advanced Ketamine therapy and SPRAVATO® treatment options for patients throughout New York City and Long Island. With locations serving Lower Manhattan and Melville, our team welcomes patients from nearby Manhattan, Brooklyn, western Suffolk County, eastern Nassau County, and surrounding communities. We help patients explore mental health services and treatment options for anxiety, depression, PTSD, OCD, Bipolar Disorder, Alcohol Dependence, and Treatment-resistant Depression (TRD) in a supportive clinical setting.

BOOK A CONSULTATION

Our protocol requires a brief intake conversation with one of our physicians to determine if ketamine is likely to help you. Please fill out the form below and you will be contacted by our Patient Care Team within 24 hours. After submitting, you’ll get the opportunity to provide more personal information via an optional questionnaire.