New York Ketamine Infusions provides physician-supervised ketamine therapy, IV ketamine infusion therapy, and SPRAVATO® (esketamine) treatment at our Manhattan clinic in New York City. We specialize in personalized treatment for eligible adults with depression and treatment-resistant depression (TRD), as well as certain other mental health conditions.
Phone: 917-261-7370
7 Days a Week: 9 AM to 7 PM
Thank you for considering New York Ketamine Infusions. We’re here to help you take the next step toward feeling better.
Have questions or want to learn more about how treatment works? Call us at 917-261-7370—we’re happy to speak with you.
You can also schedule a free Ketamine consultation at your convenience using the calendar below.
During your 1-hour virtual session, you’ll speak directly with one of our experienced doctors to explore whether ketamine therapy is the right fit for you. After booking, you’ll receive a Google Meet link via the email you provide. Please note: the provider may request additional medical information during your consultation.

Get answers to common questions about IV ketamine therapy, SPRAVATO® treatment, treatment-resistant depression, insurance coverage, costs, eligibility, and visiting New York Ketamine Infusions in Manhattan.
New York Ketamine Infusions is located at 160 Broadway, 16th Floor, New York, NY 10038 in Lower Manhattan. Our Manhattan clinic provides physician-supervised IV ketamine therapy and SPRAVATO® treatment for eligible patients. The clinic is conveniently located for patients traveling from throughout Manhattan, Brooklyn, and other areas of New York City.
Yes. New York Ketamine Infusions provides physician-supervised ketamine therapy at our Manhattan, NYC clinic, including IV ketamine infusion therapy for eligible adults. Treatment recommendations are individualized based on diagnosis, medical history, previous treatments, and clinical evaluation.
Yes. Our Manhattan clinic provides SPRAVATO® treatment in Manhattan for eligible adults with approved depression indications. SPRAVATO® contains esketamine and is administered under medical supervision. Our team can also help qualifying patients understand and verify their insurance coverage before treatment.
Our Manhattan clinic evaluates eligible adults seeking treatment for depression, treatment-resistant depression, anxiety, PTSD, OCD, bipolar depression, and certain other conditions. Treatment recommendations are individualized, and not every treatment is appropriate or indicated for every condition or patient.
Ketamine has been studied as a treatment option for adults with treatment-resistant depression, particularly when conventional antidepressant treatments have not provided adequate improvement. New York Ketamine Infusions evaluates each patient individually to determine whether IV ketamine therapy may be appropriate. Learn more about treatment-resistant depression in New York .
IV ketamine is administered intravenously in a monitored clinical setting, while SPRAVATO® contains esketamine and is administered as a nasal spray under medical supervision. SPRAVATO® is FDA-approved for specific depression indications and may be covered by insurance for eligible patients. The treatments also differ in eligibility, dosing, treatment protocols, and insurance coverage. Read our comparison of ketamine and SPRAVATO® .
Response to ketamine therapy varies from person to person. Research has found that some patients with depression may experience improvement relatively quickly compared with conventional antidepressant medications, while others may require multiple treatments or may not respond. Your NYKI provider will monitor your response throughout treatment.
The duration of improvement after ketamine treatment varies by patient. Factors may include diagnosis, treatment response, number of treatments, other therapies, and individual clinical circumstances. Some patients may require additional or maintenance treatment based on their response and their provider's recommendations.
The number and frequency of ketamine treatments depend on the patient's condition, response to treatment, medical history, and individualized treatment plan. Your NYKI provider will discuss the recommended course of treatment and evaluate your response over time.
The cost of ketamine therapy in New York City depends on the treatment recommended and the individual treatment plan. IV ketamine and SPRAVATO® also have different payment and insurance considerations. Contact New York Ketamine Infusions for current treatment-cost information and available coverage options.
Insurance coverage for IV ketamine used for psychiatric conditions differs from coverage for SPRAVATO®. Patients should verify their individual benefits and expected treatment costs before beginning therapy. Our team can explain current payment and coverage options.
Many insurance plans may cover SPRAVATO® for qualifying patients when plan requirements and medical-necessity criteria are met. Coverage varies by insurer and individual policy. New York Ketamine Infusions can help patients verify their benefits and understand potential coverage before beginning treatment. Learn more about SPRAVATO® insurance coverage .
The appropriate treatment depends on factors including your diagnosis, symptoms, previous treatments, medical history, medications, and other clinical considerations. An NYKI provider can review your history and discuss whether IV ketamine therapy, SPRAVATO®, or another treatment approach may be appropriate.
Patients receive treatment in a private, medically supervised clinical environment at our Manhattan location. The NYKI team explains the treatment process, monitoring requirements, and what to expect before, during, and after IV ketamine or SPRAVATO® treatment based on the therapy prescribed.
Patients can contact New York Ketamine Infusions to discuss consultation and eligibility requirements. Whether additional medical records, coordination with an existing mental health provider, or a referral is needed can depend on the treatment and the patient's individual circumstances.
Patients can request a consultation with New York Ketamine Infusions online or call 917-261-7370. Our Manhattan clinic is located at 160 Broadway, 16th Floor, New York, NY 10038.
Schedule a ConsultationSpeak with the New York Ketamine Infusions team about treatment options, eligibility, insurance coverage, and scheduling at our Manhattan NYC clinic.
Request a ConsultationNY Ketamine Infusions provides advanced Ketamine therapy and SPRAVATO® treatment options for patients throughout New York City and Long Island. With locations serving Lower Manhattan and Melville, our team welcomes patients from nearby Manhattan, Brooklyn, western Suffolk County, eastern Nassau County, and surrounding communities. We help patients explore mental health services and treatment options for anxiety, depression, PTSD, OCD, Bipolar Disorder, Alcohol Dependence, and Treatment-resistant Depression (TRD) in a supportive clinical setting.