LOCATIONS: NEW YORK CITY | LONG ISLAND
Book Your Consultation Now: 917-261-7370
LOCATIONS: NEW YORK CITY | LONG ISLAND
Book Your Consultation Now: 917-261-7370
SPRAVATO® is a prescription nasal spray approved by the FDA, intended to support adults who are dealing with the following conditions:
Treatment-Resistant Depression (TRD): Refers to cases where individuals have not experienced adequate relief despite undergoing a minimum of two different antidepressant treatments.
Major Depressive Disorder (MDD) accompanied by acute suicidal thoughts or actions: A rapid-response treatment option for individuals facing intense depressive episodes.
While traditional antidepressants can take several weeks to produce noticeable effects, SPRAVATO® has been shown to deliver significant relief from depressive symptoms—sometimes in as little as 24 hours.
At NY Ketamine Infusions in Melville, patients receive specialized SPRAVATO® care in a secure, compassionate environment. Experience faster relief and take the first step toward feeling like yourself again.
Response Effectiveness:
Traditional antidepressants tend to produce a favorable treatment response in approximately 40% to 60% of patients. By comparison, clinical trials involving Spravato® (esketamine) have demonstrated response rates as high as 70%, according to findings published by Popova et al. in the American Journal of Psychiatry (2019).
Speed of Relief:
While most standard antidepressant medications may take between four and six weeks before any meaningful symptom improvement is observed, clinical evidence has shown that esketamine (Spravato®) can begin alleviating depressive symptoms in as little as 24 hours (BMC Psychiatry, 2022).
Long-Term Remission Potential:
According to clinical research, 43.8% of individuals who remained on a regimen of Spravato plus an oral antidepressant at the three-month point experienced remission from their major depressive episodes.
At NY Ketamine Infusions in Melville, SPRAVATO® introduces a cutting-edge approach to treating depression. Delivered as a nasal spray under the care of skilled medical professionals, it works by interacting with NMDA receptors in the brain—often producing rapid and noticeable relief from symptoms.
Treatments are provided in our certified Melville facility, where patients are observed for a minimum of two hours after each session. This careful monitoring ensures both safety and comfort throughout the process.
1. Fast-Acting Symptom Relief
Unlike conventional antidepressants that may take weeks to show results, Spravato can begin easing symptoms within just hours or days. This rapid onset can be critical for those experiencing intense depressive episodes.
2. A Breakthrough for Treatment-Resistant Depression
Approved by the FDA, Spravato offers new hope to individuals who haven’t benefited from at least two prior antidepressant treatments—providing an option when other therapies have fallen short.
3. FDA-Approved for Depressive Symptoms in Adults With MDD and Acute Suicidal Ideation or Behavior
Clinical studies indicate that Spravato can quickly diminish suicidal ideation in individuals with major depressive disorder, delivering crucial support during urgent mental health crises.
4. A Novel Mechanism of Action
Spravato works differently from traditional antidepressants by targeting the brain’s glutamate system rather than focusing on serotonin or dopamine. This innovative approach may succeed where standard medications have not.
5. Administered in a Safe, Supervised Environment
Spravato treatment is conducted exclusively in certified medical settings, where patients are carefully monitored throughout each session. This controlled environment ensures proper dosing, safety, and immediate care if any side effects arise.
We begin with a complimentary phone consultation, then conduct a detailed review of your medical history and treatment needs to assess Spravato eligibility. If you qualify, we confirm coverage with leading insurance providers. Care is available in New York City, Long Island (Melville).
After approval, your first SPRAVATO® session will be scheduled. The nasal spray is self-administered in a comfortable, supportive clinic environment under professional supervision. Our team observes you for a minimum of two hours to safeguard your well-being and address any possible side effects.
Treatment starts with an induction phase, usually consisting of two sessions per week. Over time, this transitions into a maintenance phase with fewer appointments, personalized to match your mental health needs and support your long-term recovery goals.
We remain by your side throughout the process, offering regular check-ins to monitor progress and resolve any concerns. Your care plan adapts as needed in collaboration with your referring provider, giving you the guidance and resources required for long-term mental well-being.
Week 1-4
2 Treatments a Week
Week 5-8
1 Treatments a Week
Week 9+
1 Treatment a Week Every 1-2 Weeks
At NY Ketamine Infusions, our approach to care is rooted in the highest clinical standards. Each treatment is guided by evidence-based protocols developed and overseen by expert anesthesiologists and mental health specialists. For us, safety isn’t an added benefit, it is the core principle that shapes everything we do.
We believe healing depends not only on the treatment you receive but also on the environment where it occurs. That is why our infusion suites are created to provide calm, comfort, and privacy, offering an experience that encourages emotional ease while supporting therapeutic results. When care is delivered in a setting that feels secure, the healing process can truly begin.
We prioritize teamwork. If you are already connected with a psychiatrist, therapist, or primary care provider, we coordinate care with your consent to preserve continuity and clarity, ensuring you never have to manage your mental health journey on your own.
Innovative treatment should not be weighed down by excessive paperwork or financial barriers. At NY Ketamine Infusions, we accept insurance for eligible treatments and handle the administrative details for you, because access to healing should feel simple rather than complicated.
SPRAVATO® (esketamine) is an FDA-approved nasal spray designed for adults with treatment-resistant depression (TRD). Unlike traditional antidepressants that target serotonin and dopamine, SPRAVATO® works on NMDA receptors, helping to restore balance in brain function and providing relief for those who have not responded to standard treatments.
SPRAVATO® is intended for adults with treatment-resistant depression who have tried at least two different oral antidepressants without sufficient improvement. As of January 2025, the FDA has approved SPRAVATO® as a standalone treatment, meaning it no longer requires combination therapy with oral antidepressants. A consultation with a provider at NY Ketamine Infusions will determine if SPRAVATO® is right for you.
Each session takes place in a comfortable, supervised setting at NY Ketamine Infusions. You will self-administer the nasal spray under medical supervision. Afterward, you will be monitored for at least two hours for any potential side effects before being cleared to leave.
Many patients report feeling relief within 24 hours of their first few treatments. However, results vary, and a full treatment plan typically involves an induction phase (twice weekly for four weeks) followed by a maintenance phase based on your progress.
Common side effects include temporary dizziness, nausea, drowsiness, or dissociation (feeling detached from reality). These effects usually subside within a few hours. To ensure safety, patients are monitored closely during and after treatment.
No. Due to possible sedation and dissociation effects, you must arrange for someone to drive you home after each session. Patients should also avoid operating heavy machinery for the rest of the day.
The treatment schedule typically includes two sessions per week for the first four weeks, followed by a tapered maintenance phase depending on individual response. Your provider will tailor a plan based on your needs.
Coverage for SPRAVATO® is available through many leading insurance companies, though the extent of coverage can differ depending on your specific plan. At NY Ketamine Infusions, their dedicated team will help you confirm your insurance benefits and work to reduce your out-of-pocket expenses as much as possible.
SPRAVATO® is FDA-approved for standalone use and covered by insurance, whereas IV ketamine infusions are often out-of-pocket expenses. Additionally, SPRAVATO® is administered as a nasal spray in a certified treatment center, while ketamine infusions require an IV.
To begin treatment, schedule a consultation with NY Ketamine Infusions. Our team will evaluate your medical history, confirm eligibility, and create a personalized treatment plan to help you find relief from depression.
75 Maiden Lane, 10th Floor
New York, NY 10038
Treatment Hours:
7 days a week:
8am to 6pm
