Pain and Depression

Ny Ketamine Infusions

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Call Us 917-261-7370 or Schedule Consultation Online
75 Maiden Lane, 10th Floor, New York, Ny 10038



Depression and severe generalized anxiety can be devastating, but there is hope. For 7 years, NY Ketamine Infusions has been treating the most severe cases of depression and anxiety with low-dose ketamine infusions — with tremendous, often life-saving, success!

Citing a recent study, Cleveland Clinic noted that “Within 24 hours of receiving ketamine, 70 percent of patients with treatment-resistant depression saw an improvement in symptoms.” As a result, they designated ketamine One of The Top 10 Medical Innovations for 2017.


According to the National Institute of Mental Health, depression affects 1 in 15 adults (6.7%) annually and roughly 16.6% at some point in their life.

Common symptoms include:

  • Feeling sad
  • Loss of interest or pleasure in activities once enjoyed
  • Changes in appetite
  • Trouble sleeping or sleeping too much
  • Loss of energy / increased fatigue
  • Increase in purposeless physical activity like hand-wringing or pacing, or slowed movements and speech
  • Feeling worthless or guilty
  • Difficulty thinking, concentrating or making decisions
  • Thoughts of death or suicide


If you are visiting this website, you or someone you love are most likely dealing with a Major Depressive Disorder (MDD) that has not responded to other medication. Many of you will have tried several SSRIs, SNRIs, Tricyclic or MAOI antidepressants, or even antipsychotic medications. Some of you have undergone ECT and/or TMS with no significant improvement. Chances are that you can no longer function effectively at home, work or school, and find even small tasks — like showering or getting out of bed — insurmountable.

What you are feeling is not simply the short-lived result of one of life’s disappointments.

Severe depression, or MDD, is something quite different, and is more likely associated with feelings of intense sadness, low self-worth, and even thoughts of self-harm or suicide.

This is where NY Ketamine Infusions can help. Numerous studies at world-renowned institutions and over 7 years worth of treatment experience in our offices show that safe, low-dose ketamine infusions alleviates suffering in over 70% of patients. And unlike other anti-depressant medication, which can take 6-8 weeks to take effect, ketamine can begin to work quickly, sometimes after just one or two treatments. Over 2,400 patients thus far have experienced some form of relief from Dr. Brooks’ unique, next-level protocols and compassionate, personalized care.


Anxiety disorders also respond well to ketamine infusion therapy. Generalized anxiety is often brought on by stress and trauma and can lead to feelings of panic, heart palpitations, nausea, loss of appetite, or even a fear of dying. If you experience symptoms for a period of six months or more, you should seek a diagnosis for generalized anxiety or panic disorder. Anxiety disorders should always be treated in order to avoid worsening of symptoms or related disorders, such as depression. 

Neuropathic Pain

If you are suffering from a type of chronic pain condition that responds to ketamine, you will find that ketamine infusions can be life changing, if not life saving. Ketamine can be an effective alternative to other medications, such as opiates, painful injections, spinal cord stimulators and other therapies that have not been helpful and often cause only disappointment, frustration and unwanted side effects.

When you’ve tried everything to ease chronic pain and nothing seems to work, ketamine infusion therapy may be the answer!


First and foremost, ketamine has been used as an important human general anesthetic agent for the past five decades. Because of its versatility and safety, ketamine has been included in the World Health Organization’s list of Top 10 Essential Drugs.

For the past 25 years, ketamine — in sub-anesthetic doses — has found new importance in the treatment of mood disorders and chronic neuropathic pain conditions that have become “centralized.”


In some patients, for reasons that are unclear, injury to either peripheral nerves or the central nervous system (i.e. brain or spinal cord), causes neuroinflammation. This results in the activation of glial cells that release cytokines in the brain’s pain centers. The brain reacts through the autonomic nervous system causing chronic, intractable pain throughout the body, often accompanied by peripheral swelling, discoloration, temperature changes and allodynia (sensitivity to touch).


The traditional method for dealing with neuropathic pain is to dull the signals with prescribed pain medication, nerve blocks and other injections. Unfortunately, these treatments are often accompanied by significant, long-term side effects and do little to attack the underlying problem – they simply mask the pain.

Ketamine blocks NMDA receptors in the spinal cord. This prevents the glial cells from sending information to the brain during the infusion period. The brain stops releasing cytokines and is “rebooted.” By interrupting the process during treatment, prolonged relief of pain and other symptoms follow. Why this occurs is less clear, but ketamine does work effectively in treating most patients with central pain syndromes.

Certain types of Central Pain Syndromes are particularly responsive to ketamine therapy. They include:

  • Trigeminal Neuralgia
  • Post-herpetic Neuralgia
  • Phantom Limb Pain
  • Cluster Headaches and some Migraine Headaches
  • Complex Regional Pain Syndrome (CRPS)
  • Reflex Sympathetic Dystrophy (RSD)
  • Lyme Disease-related Pain
  • Pain following Traumatic Brain Injury or Spinal Cord Injury


If your doctors have told you that you have a central pain syndrome that is not responding to oral medications, nerve blocks or a spinal cord stimulator, we should be able to help. You or your doctor can call Dr. Brooks or one of the doctors in our satellite offices to discuss your chronic pain condition. With just a phone call, they should be able to determine if ketamine infusion therapy is likely to help you. 

(Sorry, but treatment for neuropathic pain is not available in our Madrid office.)


You may benefit from NY Ketamine Infusions’ state-of-the-art treatment if you are suffering from the conditions listed above, or any neuropathic pain that is not well controlled with injections, nerve blocks or prescription medication.



 There is finally hope for people with debilitating pain who have run out of other options. With individualized treatments based on Dr. Brooks’ unique protocols, roughly 4 out of 5 of our patients experience moderate to excellent pain relief. Ketamine’s effects can be dramatic, often allowing patients to re-engage in life’s daily activities.


We design unique treatment protocols and dosages for each of our patients, depending upon the nature of their pain and their initial response. In most cases, we will administer three infusions on three consecutive days. In cases where the diagnosis of a central pain syndrome is less certain, we will begin with one infusion to determine if ketamine will help your pain.
The ketamine is administered by slow intravenous infusion over four hours. Other medications are also administered intravenously. Each infusion is followed by a three to four hour recovery period before you are ready for discharge.
Following successful treatment, patients are generally placed on an oral ketamine supplement, and appointments for single follow-up infusions are scheduled for two, four and eight weeks after the initial series. Thereafter, patients often return for single boosters if and when they have a flare up of their pain. The intervals between boosters vary by patient and cannot be easily predicted. We see most of our patients twice a year, as needed.


 While our success rates are high, no treatment is 100% effective in treating all chronic pain. If you have one of the above conditions, however, our success rate in achieving dramatic improvement in your pain is at least 80%. With prolonged pain relief comes improved function and the probability of returning to school or work, or simply being able to once again lead a more normal, full, active life.


 Ketamine infusions are generally well-tolerated. The doses used would cause hallucinations if the ketamine was given alone. To prevent any unwanted hallucinations, we use benzodiazepines and, in some cases, propofol during the infusion. As a result, most patients comfortably doze off during the infusion and awake with no recall or unpleasant side effects.
A small number of our patients experience nausea. To prevent this possibility, we use two different antiemetics. An occasional patient will have a headache after awakening. We provide medication to alleviate this issue as well.

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